Pediatric stroke and transcranial direct current stimulation: methods for rational individualized dose optimization.

ABSTRACT:

Background

Transcranial direct current stimulation (tDCS) has been investigated mainly in adults and doses may not be appropriate in pediatric applications. In perinatal stroke where potential applications are promising, rational adaptation of dosage for children remains under investigation.

Objective

Construct child-specific tDCS dosing parameters through case study within a perinatal stroke tDCS safety and feasibility trial.

Methods

10-year-old subject with a diagnosis of presumed perinatal ischemic stroke and hemiparesis was identified. T1 magnetic resonance imaging (MRI) scans used to derive computerized model for current flow and electrode positions. Workflow using modeling results and consideration of dosage in previous clinical trials was incorporated. Prior ad

SUBMITTER: Gillick BT 

PROVIDER: S-EPMC4168687 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature