Geographic separation of domestic and wild strains of Toxoplasma gondii in French Guiana correlates with a monomorphic version of chromosome1a.

ABSTRACT:

Background

Previous studies have stressed the genetic divergence and high pathogenicity of strains of T. gondii from French Guiana. Although strains from coastal, human adapted environments (so called anthropized) resemble those found in other regions of the Caribbean, strains collected from inland jungle environment are genetically quite diverse. To better understand the composition of these distinct strain types, we undertook a more in depth analysis of T. gondii strains from French Guiana including profiling of chromosome 1a (Chr1a), which is often shared as a single monomorphic haplotype among lineages that are otherwise genetically distinct.

Methodology/principal findings

Comparison of intron sequences from selectively neutral genes indicated that anthropized strains we

SUBMITTER: Khan A 

PROVIDER: S-EPMC4169257 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature