Rapid and accurate T2 mapping from multi-spin-echo data using Bloch-simulation-based reconstruction.

ABSTRACT:

Purpose

Quantitative T2 -relaxation-based contrast has the potential to provide valuable clinical information. Practical T2 -mapping, however, is impaired either by prohibitively long acquisition times or by contamination of fast multiecho protocols by stimulated and indirect echoes. This work presents a novel postprocessing approach aiming to overcome the common penalties associated with multiecho protocols, and enabling rapid and accurate mapping of T2 relaxation values.

Methods

Bloch simulations are used to estimate the actual echo-modulation curve (EMC) in a multi-spin-echo experiment. Simulations are repeated for a range of T2 values and transmit field scales, yielding a database of simulated EMCs, which is then used to identify the T2 value whose EMC most closely match

SUBMITTER: Ben-Eliezer N 

PROVIDER: S-EPMC4169365 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature