Associations between changes in city and address specific temperature and QT interval--the VA Normative Aging Study.

ABSTRACT:

Background

The underlying mechanisms of the association between ambient temperature and cardiovascular morbidity and mortality are not well understood, particularly for daily temperature variability. We evaluated if daily mean temperature and standard deviation of temperature was associated with heart rate-corrected QT interval (QTc) duration, a marker of ventricular repolarization in a prospective cohort of older men.

Methods

This longitudinal analysis included 487 older men participating in the VA Normative Aging Study with up to three visits between 2000-2008 (n = 743). We analyzed associations between QTc and moving averages (1-7, 14, 21, and 28 days) of the 24-hour mean and standard deviation of temperature as measured from a local weather monitor, and the 24-hour mean

SUBMITTER: Mehta AJ 

PROVIDER: S-EPMC4169528 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature