The impact of delayed chemotherapy on its completion and survival outcomes in stage II colon cancer patients.

ABSTRACT:

Background

Delayed chemotherapy is associated with inferior survival in stage III colon and stage II/III rectal cancer patients, but similar studies have not been performed in stage II colon cancer patients. We investigate the association between delayed and incomplete chemotherapy, and the association of delayed chemotherapy with survival in stage II colon cancer patients.

Patients and methods

Patients (age ≥ 66) diagnosed as stage II colon cancer and received chemotherapy from 1992 to 2005 were identified from the linked SEER-Medicare database. The association between delayed and incomplete chemotherapy was assessed using unconditional and conditional logistic regressions. Survival outcomes were assessed using stratified Cox regression based on propensity score matched sam

SUBMITTER: Xu F 

PROVIDER: S-EPMC4169603 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature