Paraneoplastic pruritus presenting with Hodgkin's lymphoma: a case report.

ABSTRACT:

Introduction

Paraneoplastic pruritus is defined as pruritus that occurs before or during the natural evolution of a hematologic disease. The reported prevalence is 30% in patients with Hodgkin's lymphoma. The severity of this pruritus has a very negative impact on patients' quality of life. Very few studies have been made to examine the efficacy of pharmacological treatments for this type of pruritus. One drug that appears to be effective in this respect is off-label aprepitant, a neurokinin 1 receptor antagonist.

Case presentation

A 20-year-old Caucasian woman presented with lateral neck nodes, sweating, and pruritus and was diagnosed with stage IIB nodular sclerosis Hodgkin's lymphoma. Throughout this period during the disease the pruritus was ever-present. Improvement was

SUBMITTER: Villafranca JJ 

PROVIDER: S-EPMC4170200 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature