Ontology highlight
ABSTRACT:
SUBMITTER: Chai S
PROVIDER: S-EPMC4170635 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Chai Stella S Tong Man M Ng Kai Yu KY Kwan Pak Shing PS Chan Yuen Piu YP Fung Tsun Ming TM Lee Terence K TK Wong Nathalie N Xie Dan D Yuan Yun-Fei YF Guan Xin-Yuan XY Ma Stephanie S
Oncotarget 20140701 14
Tumor relapse after therapy typifies hepatocellular carcinoma (HCC) and is believed to be attributable to residual cancer stem cells (CSCs) that survive treatment. We have previously identified a CSC population derived from HCC that is characterized by CD133. Despite our growing knowledge of the importance of this subset of cells in driving HCC, the regulatory mechanism of CD133 is not known. Epigenetic changes are believed to be essential in the control of cancer and stem cells. Here, we report ...[more]