Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study.

ABSTRACT:

Background

Juvenile Idiopathic Arthritis (JIA) is the most common cause of non-infectious joint inflammation in children. Synovial inflammation results in pain, swelling and stiffness. Animal and adult human studies indicate that localized joint-associated inflammation may produce generalized changes in pain sensitivity. The aim was to characterize pain sensitivity in children with JIA to mechanical and thermal stimulus modalities using quantitative sensory testing (QST) at an affected inflamed joint, and compare to children in clinical remission. Generalized hypersensitivity was evaluated by comparing QST measures at the thenar eminence between JIA and healthy control children.

Methods

60 children aged 7-17 years with JIA participated. QST assessed sensory detection thresho

SUBMITTER: Cornelissen L 

PROVIDER: S-EPMC4171552 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature