Physical activity predicts microstructural integrity in memory-related networks in very old adults.

ABSTRACT:

Background

Although the beneficial effects of physical activity (PA) on memory and executive function are well established in older adults, little is known about the relationship between PA and brain microstructure and the contributions of physical functional limitations and chronic diseases. This study examined whether higher PA would be longitudinally associated with greater microstructural integrity in memory- and executive function-related networks and whether these associations would be independent of physical function and chronic diseases.

Methods

Diffusion tensor imaging was obtained in 2006-2008 in 276 participants (mean age = 83.0 years, 58.7% female, 41.3% black) with PA (sedentary, lifestyle active, and exercise active) measured in 1997-1998. Gait speed, cognition

SUBMITTER: Tian Q 

PROVIDER: S-EPMC4172036 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature