Selective assembly of DNA-conjugated single-walled carbon nanotubes from the vascular secretome.

ABSTRACT: Colloidal dispersion of single-walled carbon nanotubes (SWCNTs) is often the first processing step to many of their unique applications. However, dispersed SWCNTs often exist in kinetically trapped states where aggregation can be of concern. Recent work revealed prominent DNA-SWCNT aggregation following intravascular injection. In this study, we performed detailed analysis of DNA-SWCNT aggregate formation, structure, and composition in the context of endothelial cell condition media. Interestingly, we found that aggregates formed within condition media from cells that have undergone a stress response differ in size and organization from that of the control. We also found that temperature increases also promote DNA-SWCNT associations. A mathematical model was developed to describe the kinet

SUBMITTER: Gong X 

PROVIDER: S-EPMC4174097 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature