Neurodevelopmental changes in the responsiveness of systems involved in top down attention and emotional responding.

ABSTRACT: In this study, we aimed to investigate age related changes in systems implicated in top down attention and the implications of this for amygdala responses to emotional distracters. Fifty-one healthy subjects including 18 children (aged 10-14), 15 adolescents (aged 14-18), and 18 young adults (aged 18-25) completed the affective Stroop paradigm while undergoing functional MRI. While achieving comparable behavioral performance, children, relative to adolescents and adults, showed increased activation in areas including anterior cingulate gyrus and precentral gyrus in task relative to view trials. In addition, children showed increased activation within the amygdala and fusiform gyrus in response to emotional stimuli. Notably, the group difference within the amygdala was particularly pronounc

SUBMITTER: Hwang S 

PROVIDER: S-EPMC4175453 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature