The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations.

ABSTRACT: microRNAs (miRNAs) regulate expression by promoting degradation or repressing translation of target transcripts. miRNA target sites have been catalogued in databases based on experimental validation and computational prediction using various algorithms. Several online resources provide collections of multiple databases but need to be imported into other software, such as R, for processing, tabulation, graphing and computation. Currently available miRNA target site packages in R are limited in the number of databases, types of databases and flexibility. We present multiMiR, a new miRNA-target interaction R package and database, which includes several novel features not available in existing R packages: (i) compilation of nearly 50 million records in human and mouse from 14 different databas

SUBMITTER: Ru Y 

PROVIDER: S-EPMC4176155 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature