Transcriptome of Saccharomyces cerevisiae during production of D-xylonate.

ABSTRACT:

Background

Production of D-xylonate by the yeast S. cerevisiae provides an example of bioprocess development for sustainable production of value-added chemicals from cheap raw materials or side streams. Production of D-xylonate may lead to considerable intracellular accumulation of D-xylonate and to loss of viability during the production process. In order to understand the physiological responses associated with D-xylonate production, we performed transcriptome analyses during D-xylonate production by a robust recombinant strain of S. cerevisiae which produces up to 50 g/L D-xylonate.

Results

Comparison of the transcriptomes of the D-xylonate producing and the control strain showed considerably higher expression of the genes controlled by the cell wall integrity (CWI) pathw

SUBMITTER: Mojzita D 

PROVIDER: S-EPMC4176587 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature