Candida colonization index and subsequent infection in critically ill surgical patients: 20 years later.

ABSTRACT:

Introduction

For decades, clinicians dealing with immunocompromised and critically ill patients have perceived a link between Candida colonization and subsequent infection. However, the pathophysiological progression from colonization to infection was clearly established only through the formal description of the colonization index (CI) in critically ill patients. Unfortunately, the literature reflects intense confusion about the pathophysiology of invasive candidiasis and specific associated risk factors.

Methods

We review the contribution of the CI in the field of Candida infection and its development in the 20 years following its original description in 1994. The development of the CI enabled an improved understanding of the pathogenesis of invasive candidiasis and the us

SUBMITTER: Eggimann P 

PROVIDER: S-EPMC4176828 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature