Pediatric cancer type predicts infection rate, need for critical care intervention, and mortality in the pediatric intensive care unit.

ABSTRACT:

Purpose

Up to 38 % of children with cancer require pediatric intensive care unit (PICU) admission within 3 years of diagnosis, with reported PICU mortality of 13-27 % far exceeding that of the general PICU population. PICU outcomes data for individual cancer types are lacking and may help identify patients at risk for poor clinical outcomes.

Methods

We performed a retrospective multicenter analysis of 10,365 PICU admissions of cancer patients no greater than 21 years old among 112 PICUs between 1 January 2009 and 30 June 2012. We evaluated the effect of cancer type, age, gender, genetic syndrome, stem cell transplantation, PRISM3 score, infections, and critical care interventions on PICU mortality.

Results

After excluding scheduled perioperative admissions, cancer pat

SUBMITTER: Zinter MS 

PROVIDER: S-EPMC4177269 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature