Analysis of western lowland gorilla (Gorilla gorilla gorilla) specific Alu repeats.

ABSTRACT:

Background

Research into great ape genomes has revealed widely divergent activity levels over time for Alu elements. However, the diversity of this mobile element family in the genome of the western lowland gorilla has previously been uncharacterized. Alu elements are primate-specific short interspersed elements that have been used as phylogenetic and population genetic markers for more than two decades. Alu elements are present at high copy number in the genomes of all primates surveyed thus far. The AluY subfamily and its derivatives have been recognized as the evolutionarily youngest Alu subfamily in the Old World primate lineage.

Results

Here we use a combination of computational and wet-bench laboratory methods to assess and catalog AluY subfamily activity level and com

SUBMITTER: McLain AT 

PROVIDER: S-EPMC4177385 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature