Multimodality treatment of potentially curative gastric cancer: geographical variations and future prospects.

ABSTRACT: After much controversy, multimodality therapy is now accepted worldwide as the gold standard for treatment of resectable bulky localized gastric cancer. There is significant regional variation in the style of multimodality treatment with adjuvant chemoradiation the North American standard, neoadjuvant chemotherapy preferred in Europe and Australasia, whilst adjuvant chemotherapy is preferred in Asia. With further standardization of surgery and D1+/D2 resections increasingly accepted world wide, and in particular in the West, as the surgical standard of care for potentially curable disease, it is timely to reassess the multimodality regimes being used. The challenge in the use of multimodality therapy is how current outcomes can be standardized and improved further. Recent studies indicate

SUBMITTER: Merrett ND 

PROVIDER: S-EPMC4177471 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature