Breathprints of childhood obesity: changes in volatile organic compounds in obese children compared with lean controls.

ABSTRACT:

Objective

The objective of this study was to investigate changes in volatile organic compounds (VOCs) in exhaled breath in overweight/obese children compared with their lean counterparts.

Study design

Single exhaled breath was collected and analyzed per protocol using selective ion flow tube mass spectrometry (SIFT-MS).

Results

Sixty overweight/obese children and 55 lean controls were included. Compared with the lean group, the obese group was significantly older (14.1 ± 2.8 vs. 12.1 ± 3.0 years), taller (164.8 ± 10.9 vs. 153.3 ± 17.1 cm) and more likely to be Caucasian (60% vs. 35.2%); P < 0.05 for all. A comparison of the SIFT-MS results of the obese group with the lean group revealed differences in concentration of more than 50 compounds. A panel of four VOCs can i

SUBMITTER: Alkhouri N 

PROVIDER: S-EPMC4177515 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature