Image-based left ventricular shape analysis for sudden cardiac death risk stratification.

ABSTRACT:

Background

Low left ventricular ejection fraction (LVEF), the main criterion used in the current clinical practice to stratify sudden cardiac death (SCD) risk, has low sensitivity and specificity.

Objective

To uncover indices of left ventricular (LV) shape that differ between patients with a high risk of SCD and those with a low risk.

Methods

By using clinical cardiac magnetic resonance imaging and computational anatomy tools, a novel computational framework to compare 3-dimensional LV endocardial surface curvedness, wall thickness, and relative wall thickness between patient groups was implemented. The framework was applied to cardiac magnetic resonance data of 61 patients with ischemic cardiomyopathy who were selected for prophylactic implantable cardioverter-defibr

SUBMITTER: Vadakkumpadan F 

PROVIDER: S-EPMC4177952 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature