Overnight glucose control with an automated, unified safety system in children and adolescents with type 1 diabetes at diabetes camp.

ABSTRACT:

Objective

To determine the safety and efficacy of an automated unified safety system (USS) in providing overnight closed-loop (OCL) control in children and adolescents with type 1 diabetes attending diabetes summer camps.

Research design and methods

The Diabetes Assistant (DIAS) USS used the Dexcom G4 Platinum glucose sensor (Dexcom) and t:slim insulin pump (Tandem Diabetes Care). An initial inpatient study was completed for 12 participants to evaluate safety. For the main camp study, 20 participants with type 1 diabetes were randomized to either OCL or sensor-augmented therapy (control conditions) per night over the course of a 5- to 6-day diabetes camp.

Results

Subjects completed 54 OCL nights and 52 control nights. On an intention-to-treat basis, with glucose data

SUBMITTER: Ly TT 

PROVIDER: S-EPMC4179507 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature