Comparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis.

ABSTRACT:

Background

Visceral leishmaniasis (VL) is a deadly parasitic diseases caused by Leishmania donovani; it is a major health problem in many countries. A lack of proper understanding of the disease biology, poor diagnostic methods and increasing drug resistance are the main reasons for the growing burden of VL infection. Comparative plasma proteomics are a relatively useful technique that can be used to investigate disease-associated alterations that can help in understanding host responses against pathogens, and might be useful in disease management and diagnosis.

Result

In this study, a comparative proteomics and glycoproteomics approach using 2DE and 2D-DIGE was employed between early diagnosed VL patients of all age groups and healthy endemic and non-endemic controls in ord

SUBMITTER: Bag AK 

PROVIDER: S-EPMC4179796 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature