The role of focal therapy in the management of localised prostate cancer: a systematic review.

ABSTRACT:

Context

The incidence of localised prostate cancer is increasing worldwide. In light of recent evidence, current, radical, whole-gland treatments for organ-confined disease have being questioned with respect to their side effects, cancer control, and cost. Focal therapy may be an effective alternative strategy.

Objective

To systematically review the existing literature on baseline characteristics of the target population; preoperative evaluation to localise disease; and perioperative, functional, and disease control outcomes following focal therapy.

Evidence acquisition

Medline (through PubMed), Embase, Web of Science, and Cochrane Review databases were searched from inception to 31 October 2012. In addition, registered but not yet published trials were retrieved. Stu

SUBMITTER: Valerio M 

PROVIDER: S-EPMC4179888 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature