Reduced left executive control network functional connectivity is associated with alcohol use disorders.

ABSTRACT:

Background

Altered functional connectivity in critical networks has been associated with chronic alcohol abuse. In turn, changes in connectivity in executive control networks (ECNs) may undermine the ability to control alcohol consumption. It was hypothesized that network connectivity would be reduced in individuals with problematic alcohol use (ALC) compared with controls and that diminished network connectivity would be associated with greater failure to control drinking.

Methods

Resting-state functional magnetic resonance imaging was analyzed to identify 14 previously identified intrinsic connectivity networks (ICNs) using a priori regions of interest in cases ranging from binge drinkers to those with severe alcohol use disorder, as well as control subjects. Analyses test

SUBMITTER: Weiland BJ 

PROVIDER: S-EPMC4180110 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature