Incident long-term warfarin use and risk of osteoporotic fractures: propensity-score matched cohort of elders with new onset atrial fibrillation.

ABSTRACT:

Unlabelled

Association between warfarin use and fracture risk is unclear. We examined the association between long-term warfarin use and fracture risk at the hip, spine, and wrist in elders. No significant association was found between long-term warfarin use and fracture risk, despite biological plausibility.

Introduction

Prior studies examining the association of warfarin use and osteoporotic fractures have been conflicting, potentially related to methodological limitations. Thus, we examined the association of long-term warfarin use with risk of hip, spine, and wrist fractures among older adults with atrial fibrillation, attempting to address prior methodologic challenges.

Methods

We included men and women ≥ 65 years of age with incident atrial fibrillation and with

SUBMITTER: Misra D 

PROVIDER: S-EPMC4180421 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature