Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009-2012.

ABSTRACT:

Background

Human adenovirus 55 (HAdV-55) has caused recent outbreaks of acute respiratory disease (ARD) among adults and military trainees. The active surveillance for HAdV infections was sparse in China, and current knowledge on the HAdV-type distributions and its molecular evolution is lacking.

Objectives

To acquire better understanding on the prevalence and molecular evolution of HAdV-55 strains in China, for an informed strategy for disease control and prevention.

Population/methods

Nasopharyngeal aspirates were collected from hospitalized children with ARTI in Chongqing during 2009-2012. The genotype of HAdV isolates were determined by sequencing the partial hexon and fiber genes. Whole genome sequences of HAdV-55 were obtained for molecular evolution analysis.

SUBMITTER: Lu QB 

PROVIDER: S-EPMC4181478 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature