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Global transcriptional profiles of the copper responses in the cyanobacterium Synechocystis sp. PCC 6803.


ABSTRACT: Copper is an essential element involved in fundamental processes like respiration and photosynthesis. However, it becomes toxic at high concentration, which has forced organisms to control its cellular concentration. We have recently described a copper resistance system in the cyanobacterium Synechocystis sp. PCC 6803, which is mediated by the two-component system, CopRS, a RND metal transport system, CopBAC and a protein of unknown function, CopM. Here, we report the transcriptional responses to copper additions at non-toxic (0.3 µM) and toxic concentrations (3 µM) in the wild type and in the copper sensitive copR mutant strain. While 0.3 µM copper slightly stimulated metabolism and promoted the exchange between cytochrome c6 and plastocyanin as soluble electron carriers, the addition of

SUBMITTER: Giner-Lamia J 

PROVIDER: S-EPMC4182526 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature