Quality-of-life outcomes with coronary artery bypass graft surgery in ischemic left ventricular dysfunction: a randomized trial.

ABSTRACT:

Background

The STICH (Surgical Treatment for Ischemic Heart Failure) trial compared a strategy of routine coronary artery bypass grafting (CABG) with guideline-based medical therapy for patients with ischemic left ventricular dysfunction.

Objective

To describe treatment-related quality-of-life (QOL) outcomes, a major prespecified secondary end point in the STICH trial.

Design

Randomized trial. (ClinicalTrials.gov: NCT00023595).

Setting

99 clinical sites in 22 countries.

Patients

1212 patients with a left ventricular ejection fraction of 0.35 or less and coronary artery disease.

Intervention

Random assignment to medical therapy alone (602 patients) or medical therapy plus CABG (610 patients).

Measurements

A battery of QOL instruments at base

SUBMITTER: Mark DB 

PROVIDER: S-EPMC4182862 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature