Performance of the high-sensitivity troponin assay in diagnosing acute myocardial infarction: systematic review and meta-analysis.

ABSTRACT:

Background

High-sensitivity cardiac troponin assays have been adopted by many clinical centres worldwide; however, clinicians are uncertain how to interpret the results. We sought to assess the utility of these assays in diagnosing acute myocardial infarction (MI).

Methods

We carried out a systematic review and meta-analysis of studies comparing high-sensitivity with conventional assays of cardiac troponin levels among adults with suspected acute MI in the emergency department. We searched MEDLINE, EMBASE and Cochrane databases up to April 2013 and used bivariable random-effects modelling to obtain summary parameters for diagnostic accuracy.

Results

We identified 9 studies that assessed the use of high-sensitivity troponin T assays (n = 9186 patients). The summary sen

SUBMITTER: Al-Saleh A 

PROVIDER: S-EPMC4183183 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature