1,2-boryl migration empowers regiodivergent synthesis of borylated furans.

ABSTRACT: A regioselective transition metal-catalyzed cycloisomerization reaction of boron-containing alkynyl epoxides toward C2- and C3-borylated furans has been developed. It was found that the copper catalyst as well as the gold catalyst with more basic triflate counterion favor boryl migration toward C3-borylated furans, whereas employment of the cationic gold hexafluoroantimonate affords C2-borylated furan via a formal 1,2-hydrogen shift.

SUBMITTER: Shiroodi RK 

PROVIDER: S-EPMC4183646 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature