Overdiagnosis due to breast cancer screening: updated estimates of the Helsinki service study in Finland.

ABSTRACT:

Background

Overdiagnosis is the most important adverse event of breast cancer screening with the estimates ranging from 0% to 40-50% depending on invitational age and methods. We updated the estimates of overdiagnosis in Helsinki service screening study in Finland by comparing the observed and expected cumulative incidence of all breast carcinomas and invasive breast carcinomas.

Methods

Women aged 50-59 years have been invited to Helsinki service screening since 1986. The incidence of breast carcinoma in the first invited birth cohorts born in 1935-1939 was compared with older, non-invited cohorts. The minimum follow-up time of the invitees after the last screening round was 14 years. Expected cumulative incidence rates were estimated with two alternative approaches.

Resu

SUBMITTER: Heinavaara S 

PROVIDER: S-EPMC4183845 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature