GroopM: an automated tool for the recovery of population genomes from related metagenomes.
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ABSTRACT:
SUBMITTER: Imelfort M
PROVIDER: S-EPMC4183954 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
GroopM: an automated tool for the recovery of population genomes from related metagenomes.
Imelfort Michael M Parks Donovan D Woodcroft Ben J BJ Dennis Paul P Hugenholtz Philip P Tyson Gene W GW
PeerJ 20140930
Metagenomic binning methods that leverage differential population abundances in microbial communities (differential coverage) are emerging as a complementary approach to conventional composition-based binning. Here we introduce GroopM, an automated binning tool that primarily uses differential coverage to obtain high fidelity population genomes from related metagenomes. We demonstrate the effectiveness of GroopM using synthetic and real-world metagenomes, and show that GroopM produces results co ...[more]
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