Prostate cancer chemoprevention in men of African descent: current state of the art and opportunities for future research.

ABSTRACT: Prostate cancer is the most frequently diagnosed malignancy in men. However, African American/Black men are 60 % more likely to be diagnosed with and 2.4 times more likely to die from prostate cancer, compared to Non-Hispanic White men. Despite the increased burden of this malignancy, no evidence-based recommendation regarding prostate cancer screening exists for the high-risk population. Moreover, in addition to screening and detection, African American men may constitute a prime population for chemoprevention. Early detection and chemoprevention may thus represent an integral part of prostate cancer control in this population. Importantly, recent research has elucidated biological differences in the prostate tumors of African American compared to European American men. The latter may ena

SUBMITTER: Chornokur G 

PROVIDER: S-EPMC4184029 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature