Validation of the peroneal nerve test to diagnose critical illness polyneuropathy and myopathy in the intensive care unit: the multicentre Italian CRIMYNE-2 diagnostic accuracy study.

ABSTRACT:

Objectives

To evaluate the accuracy of the peroneal nerve test (PENT) in the diagnosis of critical illness polyneuropathy (CIP) and myopathy (CIM) in the intensive care unit (ICU). We hypothesised that abnormal reduction of peroneal compound muscle action potential (CMAP) amplitude predicts CIP/CIM diagnosed using a complete nerve conduction study and electromyography (NCS-EMG) as a reference diagnostic standard.

Design

prospective observational study.

Setting

Nine Italian ICUs.

Patients

One-hundred and twenty-one adult (≥18 years) neurologic (106) and non-neurologic (15) critically ill patients with an ICU stay of at least 3 days.

Interventions

None.

Measurements and main results

PATIENTS underwent PENT and NCS-EMG testing on the same day conduct

SUBMITTER: Latronico N 

PROVIDER: S-EPMC4184363 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature