Metabolic health reduces risk of obesity-related cancer in framingham study adults.

ABSTRACT:

Background

It is unknown whether the risk for obesity-related cancers differs between metabolically unhealthy and healthy overweight/obese adults.

Methods

Data on body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), and random blood glucose in Framingham Heart Study adults (n = 3,763) ages 55 to 69 years were used to estimate risks of obesity-related cancers (n = 385), including postmenopausal breast, female reproductive, colon, liver, gallbladder, pancreas, and kidney cancers, as well as esophageal adenocarcinomas. Multivariable-adjusted Cox proportional hazards models were used to estimate risk for obesity-related cancers associated with body fat and metabolic health (as defined by glucose levels) among subjects in three risk groups (vs. referent

SUBMITTER: Moore LL 

PROVIDER: S-EPMC4184957 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature