Intraoperative near-infrared imaging can identify pulmonary nodules.

ABSTRACT:

Background

Over 80,000 people undergo pulmonary resection for a lung nodule in the United States each year. Small nodules are frequently missed or difficult to find despite preoperative imaging. We hypothesized that near-infrared (NIR) imaging technology could be used to identify and locate lung nodules during surgery.

Methods

We enrolled 18 patients who were diagnosed with a pulmonary nodule that required resection. All patients had a fine-cut 1-mm computed tomography scan preoperatively. The patients were given systemic 5 mg/kg indocyanine green and then underwent an open thoracotomy 24 hours later. The NIR imaging was used to identify the primary nodule and search for additional nodules that were not found by visual inspection or manual palpation of the ipsilateral lung.<

SUBMITTER: Okusanya OT 

PROVIDER: S-EPMC4185369 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature