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Up-to-date approach to manage keloids and hypertrophic scars: a useful guide.


ABSTRACT: Keloids and hypertrophic scars occur anywhere from 30 to 90% of patients, and are characterized by pathologically excessive dermal fibrosis and aberrant wound healing. Both entities have different clinical and histochemical characteristics, and unfortunately still represent a great challenge for clinicians due to lack of efficacious treatments. Current advances in molecular biology and genetics reveal new preventive and therapeutical options which represent a hope to manage this highly prevalent, chronic and disabling problem, with long-term beneficial outcomes and improvement of quality of life. While we wait for these translational clinical products to be marketed, however, it is imperative to know the basics of the currently existing wide array of strategies to deal with excessive scars

SUBMITTER: Arno AI 

PROVIDER: S-EPMC4186912 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature