Calcium micro-depositions in jugular truncular venous malformations revealed by Synchrotron-based XRF imaging.

ABSTRACT: It has been recently demonstrated that the internal jugular vein may exhibit abnormalities classified as truncular venous malformations (TVMs). The investigation of possible morphological and biochemical anomalies at jugular tissue level could help to better understand the link between brain venous drainage and neurodegenerative disorders, recently found associated with jugular TVMs. To this end we performed sequential X-ray Fluorescence (XRF) analyses on jugular tissue samples from two TVM patients and two control subjects, using complementary energies at three different synchrotrons. This investigation, coupled with conventional histological analyses, revealed anomalous micro-formations in the pathological tissues and allowed the determination of their elemental composition. Rapid XRF an

SUBMITTER: Pascolo L 

PROVIDER: S-EPMC4187013 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature