Obstructive sleep apnea and sickle cell anemia.

ABSTRACT:

Objective

To ascertain the prevalence of and risk factors for obstructive sleep apnea syndrome (OSAS) in children with sickle cell anemia (SCA).

Methods

Cross-sectional baseline data were analyzed from the Sleep and Asthma Cohort Study, a multicenter prospective study designed to evaluate the contribution of sleep and breathing abnormalities to SCA-related morbidity in children ages 4 to 18 years, unselected for OSAS symptoms or asthma. Multivariable logistic regression assessed the relationships between OSAS status on the basis of overnight in-laboratory polysomnography and putative risk factors obtained from questionnaires and direct measurements.

Results

Participants included 243 children with a median age of 10 years; 50% were boys, 99% were of African heritage, a

SUBMITTER: Rosen CL 

PROVIDER: S-EPMC4187233 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature