The underlying structure of adaptation under strong selection in 12 experimental yeast populations.

ABSTRACT: The aims of this study were to determine (i) whether adaptation under strong selection occurred through mutations in a narrow target of one or a few nucleotide sites or a broad target of numerous sites and (ii) whether the programs of adaptation previously observed from three experimental populations were unique or shared among populations that underwent parallel evolution. We used archived population samples from a previous study, representing 500 generations of experimental evolution in 12 populations under strong selection, 6 populations in a high-salt environment and 6 populations in a low-glucose environment. Each set of six populations included four with sexual reproduction and two with exclusively asexual reproduction. Populations were sampled as resequenced genomes of 115 individua

SUBMITTER: Kohn LM 

PROVIDER: S-EPMC4187625 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature