Comparison of amplicor and GeneXpert MTB/RIF tests for diagnosis of tuberculous meningitis.

ABSTRACT: There are no data about the comparative accuracy of commercially available nucleic acid amplification tests (GeneXpert MTB/RIF and Roche Amplicor) for the diagnosis of tuberculous meningitis (TBM). A total of 148 patients with suspected TBM were evaluated, and cultures served as the reference standard. The sensitivities and specificities (95% confidence interval [CI]) for the Amplicor and Xpert MTB/RIF tests were similar: 46 (31-60) versus 50 (33-67) and 99 (93-100) and 94 (84-99), respectively.

SUBMITTER: Patel VB 

PROVIDER: S-EPMC4187777 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature