Cognitive impairment and risk of future stroke: a systematic review and meta-analysis.

ABSTRACT:

Background

Several studies have assessed the link between cognitive impairment and risk of future stroke, but results have been inconsistent. We conducted a systematic review and meta-analysis of cohort studies to determine the association between cognitive impairment and risk of future stroke.

Methods

We searched MEDLINE and Embase (1966 to November 2013) and conducted a manual search of bibliographies of relevant retrieved articles and reviews. We included cohort studies that reported multivariable adjusted relative risks and 95% confidence intervals or standard errors for stroke with respect to baseline cognitive impairment.

Results

We identified 18 cohort studies (total 121 879 participants) and 7799 stroke events. Pooled analysis of results from all studies showe

SUBMITTER: Lee M 

PROVIDER: S-EPMC4188684 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature