JChIP: a graphical environment for exploratory ChIP-Seq data analysis.

ABSTRACT:

Background

Chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-Seq) provides a powerful tool for discovering protein-DNA interactions. Still, the computational analysis of the great amount of ChIP-Seq data generated, involving mapping of raw data to reference genome, has been a bottle neck for most of researchers in the transcriptional and epigenetic fields. Thus, user-friendly ChIP-Seq processing method sare much needed to enable greater community of computational and bench biologists to exploit the power of ChIP-Seq technology .

Findings

jChIP is a graphical tool that was developed to analyze and display ChIP-Seq data. It matches reads to the corresponding loci downloaded from Ensembl Genes or Ensembl Regulation databases. jChIP provides a friendly

SUBMITTER: Chojnowski K 

PROVIDER: S-EPMC4189168 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature