Ontology highlight
ABSTRACT:
SUBMITTER: Wang NY
PROVIDER: S-EPMC4192050 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Wang Nai-Yu NY Patras Kathryn A KA Seo Ho Seong HS Cavaco Courtney K CK Rösler Berenice B Neely Melody N MN Sullam Paul M PM Doran Kelly S KS
The Journal of infectious diseases 20140311 6
Group B streptococcus (GBS) can cause severe disease in susceptible hosts, including newborns, pregnant women, and the elderly. GBS serine-rich repeat (Srr) surface glycoproteins are important adhesins/invasins in multiple host tissues, including the vagina. However, exact molecular mechanisms contributing to their importance in colonization are unknown. We have recently determined that Srr proteins contain a fibrinogen-binding region (BR) and hypothesize that Srr-mediated fibrinogen binding may ...[more]