Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment.

ABSTRACT:

Background

Adult house flies, Musca domestica L., are mechanical vectors of more than 100 devastating diseases that have severe consequences for human and animal health. House fly larvae play a vital role as decomposers of animal wastes, and thus live in intimate association with many animal pathogens.

Results

We have sequenced and analyzed the genome of the house fly using DNA from female flies. The sequenced genome is 691 Mb. Compared with Drosophila melanogaster, the genome contains a rich resource of shared and novel protein coding genes, a significantly higher amount of repetitive elements, and substantial increases in copy number and diversity of both the recognition and effector components of the immune system, consistent with life in a pathogen-rich environment. Ther

SUBMITTER: Scott JG 

PROVIDER: S-EPMC4195910 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature