Ontology highlight
ABSTRACT:
SUBMITTER: Wasielewski M
PROVIDER: S-EPMC4195921 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wasielewski Marijke M van Spaendonck-Zwarts Karin Y KY Westerink Nico-Derk L ND Jongbloed Jan D H JD Postma Aleida A Gietema Jourik A JA van Tintelen J Peter JP van den Berg Maarten P MP
Open heart 20140718 1
<h4>Objective</h4>Anthracyclines are successfully used in cancer treatment, but their use is limited by their cardiotoxic side effects. Several risk factors for anthracycline-associated cardiomyopathy (AACM) are known, yet the occurrence of AACM in the absence of these known risk factors suggests that other factors must play a role. The purpose of this study was to evaluate whether a genetic predisposition for dilated cardiomyopathy (DCM) could be a potential risk factor for AACM.<h4>Methods</h4 ...[more]