Maternal and cord blood 25(OH)-vitamin D concentrations in relation to child development and behaviour.

ABSTRACT:

Background

Animal studies have linked in utero vitamin D exposure to various aspects of offspring brain development. Limited research has translated these findings to humans, and none have employed cord blood to measure exposure late in gestation.

Methods

Our objective was to examine the associations between maternal 25(OH)D measured at ≤26 weeks' gestation or cord blood 25(OH)D and offspring global development, IQ, achievement, and behaviour in the US Collaborative Perinatal Project (1959-73). This was a secondary analysis of data from a case-cohort study, with 3896 women and children who participated in at least one outcome assessment. Psychologists assessed global development at 8 months, IQ and behaviour at 4 and 7 years, and achievement at 7 years. Multiple linear and l

SUBMITTER: Keim SA 

PROVIDER: S-EPMC4196708 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature