Short repetition time multiband echo-planar imaging with simultaneous pulse recording allows dynamic imaging of the cardiac pulsation signal.

ABSTRACT:

Purpose

Recently developed simultaneous multislice echo-planar imaging (EPI) sequences permit imaging of the whole brain at short repetition time (TR), allowing the cardiac fluctuations to be fully sampled in blood-oxygen-level dependent functional MRI (BOLD fMRI). A novel low computational analytical method was developed to dynamically map the passage of the pulsation signal through the brain and visualize the whole cerebral vasculature affected by the pulse signal. This algorithm is based on a simple combination of fast BOLD fMRI and the scanner's own built-in pulse oximeter.

Methods

Multiple, temporally shifted copies of the pulse oximeter data (with 0.08 s shifting step and coverage of a 1-s span) were downsampled and used as cardiac pulsation regressors in a general lin

SUBMITTER: Tong Y 

PROVIDER: S-EPMC4198428 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature