Rhipicephalus (Boophilus) microplus aquaporin as an effective vaccine antigen to protect against cattle tick infestations.

ABSTRACT:

Background

Vaccination as a control method against the cattle tick, Rhipicephalus (Boophilus) microplus has been practiced since the introduction of two products in the mid-1990s. There is a need for a vaccine that could provide effective control of R. microplus in a more consistent fashion than existing products. During our transcriptome studies of R. microplus, several gene coding regions were discovered to encode proteins with significant amino acid similarity to aquaporins.

Methods

A cDNA encoding an aquaporin from the cattle tick, Rhipicephalus microplus, was isolated from transcriptomic studies conducted on gut tissues dissected from fully engorged adult female R. microplus.

Results

Bioinformatic analysis indicates this aquaporin, designated RmAQP1, shows greate

SUBMITTER: Guerrero FD 

PROVIDER: S-EPMC4200143 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature