Design, synthesis, and application of tartaric acid derived N-spiro quaternary ammonium salts as chiral phase-transfer catalysts.

ABSTRACT: A novel class of tartaric acid-derived N-spiro quaternary ammonium salts was synthesised starting from known TADDOLs. These compounds were found to catalyse the asymmetric α-alkylation of glycine Schiff bases with high enantioselectivities and in good yields.

SUBMITTER: Waser M 

PROVIDER: S-EPMC4202190 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature