Whole-genome sequence analysis of the naturally competent Acinetobacter baumannii clinical isolate A118.

ABSTRACT: Recent studies have demonstrated a high genomic plasticity in Acinetobacter baumannii, which may explain its high capacity to acquire multiple antibiotic resistance determinants and to survive in the hospital environment. Acinetobacter baumannii strain A118 (Ab A118) was isolated in the year 1995 from a blood culture of an intensive care unit patient. As this particular strain showed some peculiar characteristic such as being naturally competent and susceptible to numerous antibiotics, we performed whole-genome comparison (WGC) studies to gain insights into the nature and extent of the genomic differences. The Ab A118 genome is approximately 3,824 kb long with a 38.4% GC content and contains 3,520 coding sequences. WGC studies showed that the Ab A118 genome has 98% average nucleotide ident

SUBMITTER: Traglia GM 

PROVIDER: S-EPMC4202317 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature